SPDY is a protocol made by Google (who else) for transporting web content faster. It tries to solve the issue of reducing latency over SSL but maintaining the security that SSL traffic brings to an site. Recently Google announced that they would join forces and merge SPDY with HTTP/2. Where does that leave you?
Reverse proxy caching is something that is almost a must have for any popular site today. For Drupalers Varnish is by far the most used reverse proxy since it's easy to use and works really well/stable. Nginx has been succesful as a reverse proxy with Drupal as well, but it has mainly been been used with the file system and modules like Boost. But there exists a Memcache module that can speak directly to Nginx as well. In this article I will do some benchmarking on how to save the data when applying memcache to Nginx.